Muscle strength and gait speed rather than lean mass are better indicators for poor cognitive function in older men Sui, Sophia X., Holloway-Kew, Kara L., Hyde, Natalie K., Williams, Lana J., Leach, Sarah and Pasco, Julie A. 2020, Muscle strength and gait speed rather than lean mass are better indicators for poor cognitive function in older men, Scientific Reports, vol. 10, no. 1, pp. 1-9, doi: 10.1038/s41598-020-67251-8. Attached Files Name Description MIMEType Size Downloads sui-musclestrengthandgait-2020.pdf Published version application/pdf 1.13MB 7 Title Muscle strength and gait speed rather than lean mass are better indicators for poor cognitive function in older men Author(s) Sui, Sophia X. orcid.org/0000-0001-6388-1261 Holloway-Kew, Kara L. orcid.org/0000-0001-5064-2990 Hyde, Natalie K. orcid.org/0000-0002-0693-2904 Williams, Lana J. orcid.org/0000-0002-1377-1272 Leach, Sarah Pasco, Julie A. orcid.org/0000-0002-8968-4714 Journal name Scientific Reports Volume number 10 Issue number 1 Article ID 10367 Start page 1 End page 9 Total pages 9 Publisher Nature Research Place of publication Berlin, Germany Publication date 2020-06-25 ISSN 2045-2322 Keyword(s) Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics COGSTATE BRIEF BATTERY ELDERLY-WOMEN SARCOPENIA IMPAIRMENT DECLINE PERFORMANCE HEALTHY ADULTS EPIDEMIOLOGY FRAILTY Summary We aimed to examine muscle strength, function and mass in relation to cognition in older men. This cross-sectional data-set included 292 men aged ≥60 yr. Handgrip strength (kg) was measured by dynamometry, gait speed by 4-metre walk (m/s) and appendicular lean mass (kg) by dual-energy x-ray absorptiometry. Cognition was assessed across four domains: psychomotor function, attention, visual learning and working memory. Composite scores for overall cognition were calculated. Bivariate analyses indicated that handgrip strength and gait speed were positively associated with cognitive function. After accounting for confounders, positive associations between individual muscle (or physical) measures and cognitive performance were sustained for handgrip strength and psychomotor function, gait speed and psychomotor function, gait speed and attention, handgrip strength and overall cognition, and gait speed and overall cognition. In multivariable models, handgrip strength and gait speed independently predicted psychomotor function and overall cognition. No associations were detected between lean mass and cognition after adjusting for confounders. Thus, low muscle strength and slower gait speed, rather than low lean mass, were associated with poor cognition in older men. Language eng DOI 10.1038/s41598-020-67251-8 Indigenous content off HERDC Research category C1 Refereed article in a scholarly journal Copyright notice ©2020, The Author(s) Free to Read? Yes Use Rights Persistent URL http://hdl.handle.net/10536/DRO/DU:30139505 Document type: Journal Article Collections: Faculty of Health School of Medicine Open Access Collection Related Links Link Description Link to full-text (open access)     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au. Versions Version Filter Type Thu, 02 Jul 2020, 14:11:02 EST Fri, 03 Jul 2020, 05:01:28 EST Sat, 01 Aug 2020, 02:31:17 EST Tue, 12 Jan 2021, 05:04:40 EST Mon, 08 Feb 2021, 08:34:41 EST Mon, 08 Feb 2021, 08:36:39 EST Filtered Full Citation counts:   Cited 3 times in TR Web of Science Cited 2 times in Scopus Search Google Scholar Access Statistics: 14 Abstract Views, 7 File Downloads  -  Detailed Statistics Created: Thu, 02 Jul 2020, 14:11:02 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.