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LC-ESI-QTOF-MS/MS characterization of seaweed phenolics and their antioxidant potential

Zhong, Biming, Robinson, Nicholas A., Warner, Robyn D., Barrow, Colin J., Dunshea, Frank R. and Suleria, Hafiz A.R. 2020, LC-ESI-QTOF-MS/MS characterization of seaweed phenolics and their antioxidant potential, Marine drugs, vol. 18, no. 6, pp. 1-21, doi: 10.3390/md18060331.

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Title LC-ESI-QTOF-MS/MS characterization of seaweed phenolics and their antioxidant potential
Author(s) Zhong, Biming
Robinson, Nicholas A.
Warner, Robyn D.
Barrow, Colin J.ORCID iD for Barrow, Colin J. orcid.org/0000-0002-2153-7267
Dunshea, Frank R.
Suleria, Hafiz A.R.ORCID iD for Suleria, Hafiz A.R. orcid.org/0000-0002-2450-0830
Journal name Marine drugs
Volume number 18
Issue number 6
Article ID 331
Start page 1
End page 21
Total pages 21
Publisher MDPI AG
Place of publication Basel, Switzerland
Publication date 2020-06
ISSN 1660-3397
Keyword(s) HPLC-PDA
LC-ESI-QTOF-MS/MS
antioxidant potential
polyphenols
seaweeds
Summary Seaweed is an important food widely consumed in Asian countries. Seaweed has a diverse array of bioactive compounds, including dietary fiber, carbohydrate, protein, fatty acid, minerals and polyphenols, which contribute to the health benefits and commercial value of seaweed. Nevertheless, detailed information on polyphenol content in seaweeds is still limited. Therefore, the present work aimed to investigate the phenolic compounds present in eight seaweeds [Chlorophyta (green), Ulva sp., Caulerpa sp. and Codium sp.; Rhodophyta (red), Dasya sp., Grateloupia sp. and Centroceras sp.; Ochrophyta (brown), Ecklonia sp., Sargassum sp.], using liquid chromatography electrospray ionization quadrupole time-of-flight mass spectrometry (LC-ESI-QTOF-MS/MS). The total phenolic content (TPC), total flavonoid content (TFC) and total tannin content (TTC) were determined. The antioxidant potential of seaweed was assessed using a 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay, a 2,2′-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) free radical scavenging assay and a ferric reducing antioxidant power (FRAP) assay. Brown seaweed species showed the highest total polyphenol content, which correlated with the highest antioxidant potential. The LC-ESI-QTOF-MS/MS tentatively identified a total of 54 phenolic compounds present in the eight seaweeds. The largest number of phenolic compounds were present in Centroceras sp. followed by Ecklonia sp. and Caulerpa sp. Using high-performance liquid chromatography-photodiode array (HPLC-PDA) quantification, the most abundant phenolic compound was p-hydroxybenzoic acid, present in Ulva sp. at 846.083 ± 0.02 μg/g fresh weight. The results obtained indicate the importance of seaweed as a promising source of polyphenols with antioxidant properties, consistent with the health potential of seaweed in food, pharmaceutical and nutraceutical applications.
Language eng
DOI 10.3390/md18060331
Indigenous content off
Field of Research 1115 Pharmacology and Pharmaceutical Sciences
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30139768

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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.