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Vitamin D and physical activity status: Associations with five-year changes in body composition and muscle function in community-dwelling older adults

Scott, David, Ebeling, Peter R., Sanders, Kerrie M., Aitken, Dawn, Winzenberg, Tania and Jones, Graeme 2015, Vitamin D and physical activity status: Associations with five-year changes in body composition and muscle function in community-dwelling older adults, Journal of Clinical Endocrinology and Metabolism, vol. 100, no. 2, pp. 670-678, doi: 10.1210/jc.2014-3519.

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Title Vitamin D and physical activity status: Associations with five-year changes in body composition and muscle function in community-dwelling older adults
Author(s) Scott, DavidORCID iD for Scott, David orcid.org/0000-0001-5226-1972
Ebeling, Peter R.
Sanders, Kerrie M.
Aitken, Dawn
Winzenberg, Tania
Jones, Graeme
Journal name Journal of Clinical Endocrinology and Metabolism
Volume number 100
Issue number 2
Start page 670
End page 678
Total pages 9
Publisher Oxford University Press
Place of publication Cary, N.C.
Publication date 2015-02-01
ISSN 0021-972X
1945-7197
Keyword(s) Science & Technology
Life Sciences & Biomedicine
Endocrinology & Metabolism
RANDOMIZED CONTROLLED-TRIAL
D SUPPLEMENTATION
25-HYDROXYVITAMIN D
AMBULATORY ACTIVITY
MASS SARCOPENIA
STRENGTH
EXERCISE
SKELETAL
BONE
ACCELEROMETER
Summary Abstract

Context:High vitamin D and physical activity (PA) levels are independently associated with improved body composition and muscle function in older adults.

Objective:The objective of this study was to investigate the interaction of 25-hydroxyvitamin D (25OHD) and PA status in maintenance of body composition and muscle function in older adults.

Design and Setting:This was a 5-year prospective population-based study of Australian community-dwelling older adults.Participants:

Participants in the study included 615 community-dwelling volunteers aged 50 years old or older [61.4 ± 6.9 (mean ± SD) y; 48% female] randomly selected from electoral rolls and categorized according to baseline serum 25OHD (≥ or <50 nmol/L) and PA (≥ or <10 000 pedometer determined steps/d) levels as follows: high 25OHD and high PA (VitD+PA+); high 25OHD and low PA (VitD+PA−); low 25OHD and high PA (VitD-PA+); and low 25OHD and low PA (VitD-PA−). A subset of 518 participants completed accelerometer assessments during follow-up.

Main Outcome Measures:Changes in dual-energy X-ray absorptiometry-assessed body composition and lower-limb muscle function were measured.

Results:VitD+PA+ had significantly smaller increases in body fat over 5 years compared with other groups (all P < .05). Higher baseline pedometer-determined PA resulted in declines in total body fat (β = −.23 kg per 100 steps/d, P = .001) over 5 years for participants with high 25OHD but not those with low 25OHD (P > .05). Among participants with accelerometer data, these associations were generally mediated by higher levels of moderate/vigorous PA.

Conclusions:High vitamin D status appears to enhance PA-related declines in body fat during aging, but the mechanism may be greater amounts of outdoor moderate/vigorous PA rather than a direct effect of 25OHD.
Language eng
DOI 10.1210/jc.2014-3519
Indigenous content off
Field of Research 1103 Clinical Sciences
1114 Paediatrics and Reproductive Medicine
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2015, Endocrine Society
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30139913

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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.