Developmental strategies of curcumin solid dispersions for enhancing bioavailability Tran, Ha Lien Phuong and Tran, TTD 2020, Developmental strategies of curcumin solid dispersions for enhancing bioavailability, Anti-Cancer Agents in Medicinal Chemistry, vol. 20, no. 16, pp. 1874-1882, doi: 10.2174/1871520620666200708103845. Title Developmental strategies of curcumin solid dispersions for enhancing bioavailability Author(s) Tran, Ha Lien Phuong orcid.org/0000-0001-8463-7516 Tran, TTD Journal name Anti-Cancer Agents in Medicinal Chemistry Volume number 20 Issue number 16 Start page 1874 End page 1882 Total pages 9 Publisher Bentham Science Publishers Ltd. Place of publication San Francisco, Calif. Publication date 2020 ISSN 1871-5206 1875-5992 Keyword(s) Solid dispersion bioavailability chemical stability drug delivery nanoparticle poorly water-soluble drug Summary Background:Although curcumin has been demonstrated to be beneficial in treating various diseases,its low solubility, chemical stability and bioavailability limit its application, especially in cancer therapy.Methods:Solid dispersions have been utilized in the last few decades to improve the bioavailability and stabilityof curcumin.Results:However, there is a lack of summaries and classifications of the methods for preparing curcumin withthis technology. The current review aims to overview the strategies used to develop solid dispersions containingcurcumin for improving drug delivery. The classification of techniques for creating solid dispersions for curcuminwas summarized, including systems for protecting curcumin degradation despite its chemical stability. Theapplications of advanced nanotechnologies in recent studies of solid dispersions were also discussed to explainthe roles of nanoparticles in formulations.Conclusion:This overview of recent developments in formulating solid dispersions for improving curcuminbioavailability will contribute to future studies of curcumin for clinical development. Language eng DOI 10.2174/1871520620666200708103845 Indigenous content off Field of Research 0304 Medicinal and Biomolecular Chemistry 1112 Oncology and Carcinogenesis HERDC Research category C1 Refereed article in a scholarly journal Persistent URL http://hdl.handle.net/10536/DRO/DU:30141729 Document type: Journal Article Collections: Faculty of Health School of Medicine Related Links Link Description Connect to published version Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Fri, 11 Sep 2020, 14:56:32 EST Sat, 12 Sep 2020, 05:02:00 EST Sat, 26 Sep 2020, 02:31:50 EST Tue, 12 Jan 2021, 05:08:18 EST Mon, 25 Jan 2021, 13:54:21 EST Mon, 25 Jan 2021, 13:55:33 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Cited 0 times in Scopus Search Google Scholar Access Statistics: 10 Abstract Views  -  Detailed Statistics Created: Fri, 11 Sep 2020, 14:56:32 EST

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