Mucoadhesive Formulation Designs for Oral Controlled Drug Release at the Colon Tran, Ha Lien Phuong and Tran, Thao T.D. 2021, Mucoadhesive Formulation Designs for Oral Controlled Drug Release at the Colon, Current Pharmaceutical Design, vol. 27, no. 4, doi: 10.2174/1381612826666200917143816. Title Mucoadhesive Formulation Designs for Oral Controlled Drug Release at the Colon Author(s) Tran, Ha Lien Phuong orcid.org/0000-0001-8463-7516 Tran, Thao T.D. Journal name Current Pharmaceutical Design Volume number 27 Issue number 4 Publisher Bentham Science Publishers Ltd. Place of publication Schiphol, The Netherlands Publication date 2021 ISSN 1381-6128 1873-4286 Keyword(s) colonic delivery controlled release mucoadhesivematrices. mucoadhesive drug delivery system mucoadhesive nanoparticles Summary :Mucoadhesive formulations have been demonstrated to result in efficient drug delivery systems with advantagesover existing systems such as increased local retention and sustained drug release via adhesiveness to mucosal tissues. Thecontrolled release of colon-targeted, orally administered drugs has recently attracted a number of studies investigatingmucoadhesive systems. Consequently, substantial designs, from mucoadhesive cores to shells of particles, have been studiedwith promising applications. This review will provide an overview of and discuss specific strategies for developingmucoadhesive systems for colon-targeted oral delivery with controlled drug release, including mucoadhesive matrices,cross-linked mucoadhesive microparticles, coatings and mucoadhesive nanoparticles. The understanding of the basicprinciple of these designs and advanced formulations throughout will lead to the development of products with efficientdrug delivery at the colon for therapies for different diseases. Language eng DOI 10.2174/1381612826666200917143816 Indigenous content off Field of Research 1115 Pharmacology and Pharmaceutical Sciences HERDC Research category C1 Refereed article in a scholarly journal Persistent URL http://hdl.handle.net/10536/DRO/DU:30143302 Document type: Journal Article Collections: Faculty of Health School of Medicine Related Links Link Description Connect to published version Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Mon, 28 Sep 2020, 11:15:49 EST Tue, 29 Sep 2020, 05:00:35 EST Tue, 29 Sep 2020, 07:46:16 EST Wed, 13 Jan 2021, 13:23:51 EST Tue, 16 Feb 2021, 10:22:34 EST Tue, 16 Feb 2021, 10:23:58 EST Filtered Full Citation counts:   Cited 0 times in TR Web of Science Cited 0 times in Scopus Search Google Scholar Access Statistics: 8 Abstract Views  -  Detailed Statistics Created: Mon, 28 Sep 2020, 11:15:49 EST

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