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Do malignant cells sleep at night?

Cortés-Hernández, Luis Enrique, Eslami-S, Zagra, Dujon, Antoine M., Giraudeau, Mathieu, Ujvari, Beata, Thomas, Frédéric and Alix-Panabières, Catherine 2020, Do malignant cells sleep at night?, Genome Biology, vol. 21, doi: 10.1186/s13059-020-02179-w.

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Title Do malignant cells sleep at night?
Author(s) Cortés-Hernández, Luis Enrique
Eslami-S, Zagra
Dujon, Antoine M.
Giraudeau, Mathieu
Ujvari, BeataORCID iD for Ujvari, Beata orcid.org/0000-0003-2391-2988
Thomas, Frédéric
Alix-Panabières, Catherine
Journal name Genome Biology
Volume number 21
Article ID 276
Total pages 18
Publisher BioMed Central [Springer Nature]
Place of publication London, Eng.
Publication date 2020-12
ISSN 1474-7596
1474-760X
Keyword(s) Chronobiology
Circadian cycle
Circulating tumor cells
Disease ecology
Phenology
Tumor dissemination
Summary Biological rhythms regulate the biology of most, if not all living creatures, from whole organisms to their constitutive cells, their microbiota, and also parasites. Here, we present the hypothesis that internal and external ecological variations induced by biological cycles also influence or are exploited by cancer cells, especially by circulating tumor cells, the key players in the metastatic cascade. We then discuss the possible clinical implications of the effect of biological cycles on cancer progression, and how they could be exploited to improve and standardize methods used in the liquid biopsy field.
Language eng
DOI 10.1186/s13059-020-02179-w
Indigenous content off
Field of Research 05 Environmental Sciences
06 Biological Sciences
08 Information and Computing Sciences
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2020, The Authors
Free to Read? Yes
Persistent URL http://hdl.handle.net/10536/DRO/DU:30145796

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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.