1-Methyl-1 H-pyrazole-5-carboxamide derivatives exhibit unexpected acute mammalian toxicity

Preston, Sarah, Garcia-Bustos, Jose, Hall, Liam G, Martin, Sheree D, Le, Thuy G, Kundu, Abhijit, Ghoshal, Atanu, Nguyen, Nghi H, Jiao, Yaqing, Ruan, Banfeng, Xue, Lian, Huang, Fei, Chang, Bill CH, Mcgee, Sean L, Wells, Timothy NC, Palmer, Michael J, Jabbar, Abdul, Gasser, Robin B and Baell, Jonathan B 2021, 1-Methyl-1 H-pyrazole-5-carboxamide derivatives exhibit unexpected acute mammalian toxicity, Journal of medicinal chemistry, vol. 64, no. 1, pp. 840-844, doi: 10.1021/acs.jmedchem.0c01793.

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Title 1-Methyl-1 H-pyrazole-5-carboxamide derivatives exhibit unexpected acute mammalian toxicity
Author(s) Preston, Sarah
Garcia-Bustos, Jose
Hall, Liam G
Martin, Sheree D
Le, Thuy G
Kundu, Abhijit
Ghoshal, Atanu
Nguyen, Nghi H
Jiao, Yaqing
Ruan, Banfeng
Xue, Lian
Huang, Fei
Chang, Bill CH
Mcgee, Sean LORCID iD for Mcgee, Sean L orcid.org/0000-0001-6953-106X
Wells, Timothy NC
Palmer, Michael J
Jabbar, Abdul
Gasser, Robin B
Baell, Jonathan B
Journal name Journal of medicinal chemistry
Volume number 64
Issue number 1
Start page 840
End page 844
Total pages 5
Publisher American Chemical Society
Place of publication Washington, D.C.
Publication date 2021-01-14
ISSN 0022-2623
1520-4804
Keyword(s) oxygen
assays
rodent models
inhibition
toxicity
Language eng
DOI 10.1021/acs.jmedchem.0c01793
Indigenous content off
Field of Research 0304 Medicinal and Biomolecular Chemistry
0305 Organic Chemistry
1115 Pharmacology and Pharmaceutical Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Persistent URL http://hdl.handle.net/10536/DRO/DU:30146890

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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