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Study protocol for the systematic review and meta-analyses of the association between schizophrenia and bone fragility

Azimi Manavi, Behnaz, Stuart, Amanda L., Pasco, Julie A., Hodge, Jason M., Corney, Kayla, Berk, Michael and Williams, Lana J. 2020, Study protocol for the systematic review and meta-analyses of the association between schizophrenia and bone fragility, BMJ Open, vol. 10, no. 12, pp. 1-4, doi: 10.1136/bmjopen-2020-041859.

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Title Study protocol for the systematic review and meta-analyses of the association between schizophrenia and bone fragility
Author(s) Azimi Manavi, BehnazORCID iD for Azimi Manavi, Behnaz orcid.org/0000-0001-7450-1877
Stuart, Amanda L.ORCID iD for Stuart, Amanda L. orcid.org/0000-0001-8770-9511
Pasco, Julie A.ORCID iD for Pasco, Julie A. orcid.org/0000-0002-8968-4714
Hodge, Jason M.
Corney, Kayla
Berk, MichaelORCID iD for Berk, Michael orcid.org/0000-0002-5554-6946
Williams, Lana J.ORCID iD for Williams, Lana J. orcid.org/0000-0002-1377-1272
Journal name BMJ Open
Volume number 10
Issue number 12
Article ID e041859
Start page 1
End page 4
Total pages 4
Publisher BMJ
Place of publication London, Eng.
Publication date 2020-12-12
ISSN 2044-6055
2044-6055
Keyword(s) bone density
bone fragility
bone health
bone quality
fracture
mental disorders
neuroscience
osteopenia
osteoporosis
psychiatry
schizophrenia
Science & Technology
Life Sciences & Biomedicine
Medicine, General & Internal
General & Internal Medicine
MAJOR DEPRESSIVE DISORDER
OSTEOPOROTIC FRACTURES
PSYCHOTIC DISORDERS
BIPOLAR DISORDER
MINERAL DENSITY
RISK
PEOPLE
ANTIPSYCHOTICS
PREVALENCE
PROLACTIN
Summary Introduction: Individuals with schizophrenia are known to be at higher risk of comorbid conditions, both physical and psychological. Osteoporosis is possibly one of these, leading to public health concerns due to higher rates of associated mortality and morbidity. We aim to systematically search all available evidence across electronic databases regarding the relationship between schizophrenia and bone fragility. Methods and analysis: A systematic search of the research databases CINAHL, MEDLINE Complete, Embase and PsycINFO will be conducted and identified papers reviewed for eligibility, with a second reviewer confirming inclusions. Searches will be run from database inception to 1 October 2020 and supplemented by the hand checking of references of identified articles. A previously published scoring system will be used for assessing the methodological quality and risk of bias. A meta-analysis is planned. Ethics and dissemination: Due to including published literature only, ethical permission will not be necessary. Results of this study will be published in a relevant scientific journal and presented at a conference in the field of interest. PROSPERO registration number: CRD42020171959.
Language eng
DOI 10.1136/bmjopen-2020-041859
Indigenous content off
Field of Research 1103 Clinical Sciences
1117 Public Health and Health Services
1199 Other Medical and Health Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2020, The Authors
Free to Read? Yes
Use Rights Creative Commons Attribution non-commercial licence
Persistent URL http://hdl.handle.net/10536/DRO/DU:30146987

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
Open Access Collection
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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.