Hydrogen (H2) has a high potential for future energy market. Recently H2 has received significant attention for its use in various applications due to zero-emission risk. H2 can be used in applications such as; in electricity generation, in H2 fuel cell electric vehicle (FCEV), in manufacturing industries, in fertilizer production, and most promisingly in energy transportation applications in the form of liquid H2 or converting it into ammonia (NH3). H2 exists naturally with different hydrocarbons such as methane (CH4), propane (C3H8), ethane (C2H6), however during the extraction of H2 there is a scope of significant emission. Currently most H2 production is from natural gas and coal, therefore, emission still exists in the process. H2 can be produced from water by using electrolyzer. Although producing H2 from low-carbon sources using electrolyzer is still expensive, but the cost of H2 production is dropping with the use of electricity from renewable energy sources. Moreover, municipal solid waste (MSW) is a rich source of hydrocarbon and at the end of its life cycle, it goes to landfill, which results in a significant amount of emission to the air, soil, and water. This chapter presents and explains the potential of H2 generation from MSW using gasification process. Gasification is thermochemical process that can convert carbon-based feed into H2 rich syngas. The benefits of producing H2 from wastes are also reported in this chapter. The outcome of this chapter can be used for the production of clean, safe, affordable, and secure energy in the form of H2 from the abundant source of MSW.