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Identifying early warning signs, preventing relapse, and termination of therapy

posted on 2009-01-01, 00:00 authored by Craig A Macneil, Melissa K Hasty, Philippe Conus, Michael BerkMichael Berk, Jan Scott
rodromal symptoms before manic depressive relapses show considerable variation in their nature and timing between individuals … Prodromal symptoms, however, are consistent within individuals giving them a predictive value for each patient. Perry et al. (1995, p. 405–6) Research indicates that between 70% and 90% of people with bipolar disorder will have more than one episode (Keller et al.,1993; Gitlin et al., 1995; Tacchi & Scott, 2005), with naturalistic studies showing that around 49.8% of people will relapse within a year, and 68% within 2 years (Silverstone et al., 1998; Lam & Wong, 2005). Amongst those who relapse, two-thirds will have multiple relapses, with 9 being the mean number of episodes (Keller et al., 1993; Gitlin et al., 1995). Given these high rates of relapse in bipolar disorder, work on relapse prevention remains an essential aspect of psychological intervention for this population. It is encouraging that there often appear to be signs or symptoms which occur before a person becomes symptomatic, with early identification of these providing an opportunity to intervene and prevent relapse. There is also evidence that about 75% of people with bipolar disorder are themselves able to reliably identify their prodromal symptoms for both mania and depression (Jackson et al., 2003), even following a first episode (Ward et al., 2003). In their randomized treatment trial, Perry et al. (1995) found that most of the trial participants had identifiable early signs, which began between two and four weeks prior to a manic or depressive relapse.


Chapter number








Publication classification

BN.1 Other book chapter, or book chapter not attributed to Deakin




Cambridge University Press

Place of publication

Cambridge, Eng.

Title of book

Bipolar Disorder in Young People - A Psychological Intervention Manual