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Image analysis of pore size distribution in electrospun nanofiber webs: new trends and developments

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posted on 2009-01-01, 00:00 authored by Shayan Seyedin, V Mottaghitalab, A K Haghi
Nanofibers produced by electrospinning method are widely used for drug delivery, as tissue scaffolding materials and filtration purposes where specific pore characteristics are required. For continued growth in these areas, it is critical that the nanofibers be properly designed for these applications to prevent failure. Most of the current methods only provide an indirect way of determining pore structure parameters and contain inherent disadvantages. In this study, we developed a novel image analysis method for measuring pore characteristics of electrospun nanofiber webs. 5 electrospun webs with different pore characteristics were analyzed by this method. The method is direct, so fast and presents valuable and comprehensive information regarding to pore structure parameters of the webs. Two sets of simulated images were generated to study the effects of web density, fiber diameter and its variations on pore characteristics. The results indicated that web density and fiber diameter significantly influence the pore characteristics whereas the effect of fiber diameter variations was insignificant.

History

Title of book

Monomers, oligomers, polymers, composites and nanocomposites research

Chapter number

11

Pagination

167 - 184

Publisher

Nova Science Publuishers

Place of publication

Hauppage, N.Y.

ISBN-13

9781604568776

Language

eng

Publication classification

B Book chapter; B1.1 Book chapter

Copyright notice

2009, Nova Science Publishers

Extent

31

Editor/Contributor(s)

R Pethrick, G Zaikov, J Pielichowski

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