It is widely known that nurses are pivotal in coordinating and communicating patient care information in the complex network of healthcare professionals and service delivery. Yet, despite their pivotal role, information communication technologies have historically rarely been designed around nurses' operational needs. This could explain the poor integration of technologies into nursing work processes and consequent rejection by nursing professionals. The complex nature of acute care delivery in hospitals and the frequently interrupted patterns of nursing work suggest that nurses require flexible intelligent systems that can support and adapt to their variable workflow patterns. This study is designed to explore nurses' initial reactions to a new integrated point of care solution for acute healthcare contexts. We report on the first stage of a longitudinal project to use an innovative approach involving nurses in the development and refinement of this solution. Unified Theory of Acceptance and Use of Technology was used to evaluate acceptability of the proposed system by nurses.