Phineas Gage

In 1848, as the result of a bizarre accident, Phineas Gage had most of the left frontal lobe of his brain destroyed. Although his surviving the injury by some 11.5 years made him a considerable medical curiosity, it was the changes to his behavior that made him important in the neurosciences. Gage's is actually one of the most important cases in the history of the neurosciences: it revealed for the first time that complex functions might be localized in the brain. Its status is indexed by its still being cited in about two-thirds of all psychology and related neuroscience textbooks and by the fact that studies were still being undertaken some 150 years after the accident to establish which parts of Gage's brain were damaged.