Deakin University
Browse

File(s) under embargo

A Novel Feature from Instrumented Utensils for Clinical Assessment of Friedreich Ataxia

conference contribution
posted on 2024-01-08, 04:51 authored by Lahiru Laminda AbeysekaraLahiru Laminda Abeysekara, C Kolambahewage, Pubudu PathiranaPubudu Pathirana, M Horne, DJ Szmulewicz, LA Corben
Friedreich Ataxia (FRDA) is an inherited disorder that affects the cerebellum and other regions of the human nervous system. It causes impaired movement that affects quality and reduces lifespan. Clinical assessment of movement is a key part of diagnosis and assessment of severity. Recent studies have examined instrumented measurement of movement to support clinical assessments. This paper presents a frequency domain approach based on Average Band Power (ABP) estimation for clinical assessment using Inertial Measurement Unit (IMU) signals. The IMUs were attached to a 3D printed spoon and a cup. Participants used them to mimic eating and drinking activities during data collection. For both activities, the ABP of frequency components from individuals with FRDA clustered in 0 to 0.2Hz band. This suggests that the ABP of this frequency is affected by FRDA irrespective of the device or activity. The ABP in this frequency band was used to distinguish between FRDA and non-ataxic participants using the Area Under the Receiver-Operating-Characteristic Curve (AUC) which produced peak values greater than 0.8. The machine learning models (logistic regression and neural networks) produced accuracy greater than 80% with these features common to both devices.

History

Volume

2023

Pagination

1-4

Location

United States

Start date

2023-07-24

End date

2023-07-27

ISSN

2375-7477

eISSN

2694-0604

Language

eng

Publication classification

E1 Full written paper - refereed

Title of proceedings

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Event

2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)

Publisher

IEEE

Place of publication

Piscataway, N.J.