A fast-scan cyclic voltammetry device with programmable excitation waveform

© 2016 IEEE. A number of recent studies are beginning to investigate the role of Adenosine 5-Triphospate (ATP) in a number of serious neurological conditions. However, investigation into this connection has been hampered due to the difficulty of taking in-vivo ATP measurement without causing harm to the subject. The Fast-Scan Cyclic Voltammetry device presented in this paper attempts to provide a partial solution to this problem. This device is highly suited for use on animal models during pre-clinical testing as it is developed in a very small form-factor, having a surface area 85.67% smaller than the next smallest investigated device, and is the only device found that can provide sawhorse waveforms in a portable form-factor. An Android application is also developed which allows for control of the device via a wireless link. The device was found to be capable of producing excitation waveforms within the range required [-0.4V 1.5V] with a rate of change up to 1000V/s. The output waveform is highly customizable, and sample excitation waveforms for detection of neurotransmitters such as dopamine, serotonin, and ATP are presented. The device was found to be capable of continuous operation for over 24 hours on a single NiMH coin cell battery.