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Hypoallergenic variant of the major egg white allergen Gal d 1 produced by disruption of cysteine bridges

Version 2 2024-06-03, 12:44
Version 1 2016-01-20, 12:00
conference contribution
posted on 2024-06-03, 12:44 authored by PR Dhanapala, T Doran, MLK Tang, Cenk SuphiogluCenk Suphioglu
Gal d 1 (Ovomucoid) is the most allergenic protein in the chicken egg white. Hypoallergenic variants of this allergen can be used in immunotherapy as an egg allergy treatment approach. We hypothesized that disruption of selected cysteine-cysteine disulfide bridges by mutagenesis will allow us the production of a hypoallergenic variant of the protein.

History

Pagination

1-1

Location

Houston, Tex.

Start date

2015-02-20

End date

2015-02-24

Language

eng

Notes

Abstract published in Journal of allergy and clinical immunology (February 2015), Volume 135, Issue 2, Supplement, Page AB387. DOI: http://dx.doi.org/10.1016/j.jaci.2014.12.1893

Publication classification

E Conference publication, E3.1 Extract of paper

Copyright notice

2015, AAAAI

Title of proceedings

AAAAI 2015 : Proceedings of the Annual Meeting of the American Academy of Allergy Asthma and Immunology

Event

American Academy of Allergy Asthma and Immunology. Annual Meeting (2015 : Houston, Tex.)

Publisher

AAAAI

Place of publication

Milwaukee, Wis.

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