File(s) under permanent embargo

In vitro studying corrosion behaviour of biocorrodible Mg alloys

conference contribution
posted on 01.01.2012, 00:00 authored by S Jamalia, S Moulton, Maria ForsythMaria Forsyth, G Wallace
The idea of bioabsorbable/biocorrodible stents has gained increasing attention in the last decade. Permanent coronary stents, traditionally made from 316L grade stainless steel, are routinely used for the treatment of blocked arteries. However, these stents can cause complications such as restenosis, thrombosis and the need for the patient to undergo prolonged antiplatelet therapy. Biodegradable metal stents provide an opportunity for the stent to remain in place for a period to ensure restoration of function and then degrade through a carefully controlled bio-corrosion process. Among the number of potentially suitable materials, Magnesium alloys have shown great promise as a stent material due to their non-toxicity [1] and the corrosion rates attainable in biological environments. However, a carefully controlled corrosion process is essential in order to avoid hyper hydrogen generation and the fatal consequences that follow. In addition uniform corrosion is a basic requirement to maintain the mechanical integrity and load bearing characteristics. Work being undertaken in our laboratories focuses on controlling the corrosion behaviour of magnesium in a simulated biological environment in the presence of protein. In the investigation reported here the Mg alloy has been examined using Scanning Electrochemical Microscope (SECM) to visualize the corrosion process and identify the corrosion pattern. Complementary bulk electrochemical techniques (EIS and potentiodynamic polarization) have been used to acquire kinetic and mechanistic information. Early results obtained by SECM have revealed the tendency towards pitting corrosion in the early stages which subsequently develops in to filiform corrosion.

History

Event

Australasian Corrosion Association. Conference (2012 : Melbourne, Victoria)

Pagination

1 - 11

Publisher

Australasian Corrosion Association

Location

Melbourne, Victoria

Place of publication

[Melbourne, Vic.]

Start date

11/11/2012

End date

14/11/2012

ISBN-13

9781622769698

Language

eng

Publication classification

E1 Full written paper - refereed

Title of proceedings

ACA Corrosion & Prevention 2012 : Proceedings of the Annual Australasian Corrosion Association Conference