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Investigation of trapping process in 'Centrifuge-on-a-chip'

conference contribution
posted on 2023-02-07, 04:13 authored by Jun ZhangJun Zhang, M Li, W Li, G Alici
'Centrifuge-on-a-chip' is a versatile and multifunctional microfluidic chip which can conduct operations of selective trapping, enrichment, labeling and solution exchange. In this work, the mechanism of selective trapping ability was studied by both the experiments and numerical simulation. We proved the existence of shear gradient lift force in the expansion-contraction cavity and derived an explicit expression of it. Also, a numerical modeling was developed to study the trapping process of micro-particles in a 'Centrifuge-on-a-chip'. The effects of flow condition and particle size on the trapping process were investigated. It demonstrates that the derived expression and developed model are suitable for the prediction of particles' trapping process, which can assist the design of 'Centrifuge-on-a-chip'. © 2013 IEEE.

History

Pagination

1266-1271

Location

AUSTRALIA, Wollongong

Start date

2013-07-09

End date

2013-07-12

ISSN

2159-6255

ISBN-13

9781467353199

Language

English

Title of proceedings

2013 IEEE/ASME International Conference on Advanced Intelligent Mechatronics: Mechatronics for Human Wellbeing, AIM 2013

Event

IEEE/ASME International Conference on Advanced Intelligent Mechatronics (AIM) - Mechatronics for Human Wellbeing

Publisher

IEEE

Series

IEEE ASME International Conference on Advanced Intelligent Mechatronics

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