File(s) under permanent embargo
Parameter sensitivity analysis of surface plasmon resonance biosensor through numerical simulation
conference contribution
posted on 2010-01-01, 00:00 authored by Saiful Islam, Abbas KouzaniAbbas Kouzani, Xiujuan Dai, W MichalskiSurface based analytical tools have gained more importance for rapid, sensitive and label-free monitoring of molecular recognition events. Surface plasmon resonance (SPR) has played a prominent role in real time monitoring of surface binding events. SPR is increasing its significance especially for the study of ultrathin dielectric layer. This paper investigates the role of thin films of gold, silver and aluminium for protein detection in SPR biosensors. It is shown that the sensitivity, which is indicated by the shift of plasmon dip, is not linearly related to the thickness of protein but quadratic over a specific range. The approach involves a plot of a reflectivity curve as a function of the angle of incidence.
History
Event
IEEE/ICME International Conference on Complex Medical Engineering (2010 : Gold Coast, Queensland)Pagination
171 - 176Publisher
IEEELocation
Gold Coast, QueenslandPlace of publication
Gold Coast, QueenslandStart date
2010-07-13End date
2010-07-15ISBN-13
9781424468423Language
engNotes
Conference website - http://www.usq.edu.au/cme2010Publication classification
E1 Full written paper - refereedCopyright notice
2010, IEEEEditor/Contributor(s)
Y Li, J Yang, P Wen, J WuTitle of proceedings
IEEE/ICME 2010 : Proceedings of the 2010 IEEE/ICME International Conference on Complex Medical EngineeringUsage metrics
Categories
No categories selectedLicence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC