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Randomized placebo controlled trials of n-acetyl cysteine as adjunct therapy for schizophrenia and bipolar disorder

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conference contribution
posted on 2009-01-01, 00:00 authored by A Bush, Olivia DeanOlivia Dean, D Copolov, Michael BerkMichael Berk
Glutathione is the principal antioxidant of the brain. There is evidence of oxidative stress, lowered brain glutathione and genetic linkage involve glutathione metabolic genes in schizophrenia and bipolar disorder. N-acetyl cysteine (NAC) is a safe, orally bioavailable, precursor of glutathione. NAC has been shown to reverse animal models of oxidative stress, and raises brain glutathione levels.

History

Location

Paris, France

Open access

  • Yes

Start date

2009-06-28

End date

2009-07-02

Language

eng

Notes

Presented during a Free Communication sessionEvery reasonable effort has been made to ensure that permission has been obtained for items included in Deakin Research Online. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au

Publication classification

EN.1 Other conference paper

Copyright notice

2009, World Federation of Societies of Biological Psychiatry

Title of proceedings

WFSBP Congress 2009 : Proceedings of the 9th World Congress of Biological Psychiatry

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