Relationship between Angiotensin Converting Enzyme gene and Cardiac Autonomic Neuropathy among Australian population

Angiotensin Converting Enzyme (ACE) gene considers a risk factor for many pathologies such as hypertensive, and diabetic nephropathy. The objective of this study was to investigate the role of ACE genotype with Cardiovascular Autonomic Neuropathy (CAN). We used a data set for 299 participants with and without CAN, as well as with different ACE genotype. Various statistical tests have been considered. Logistic regression was applied to demonstrate the size effect of each predictor. The results revealed, there was no significant different between ACE genotype in the patients with and without CAN. Logistic regression demonstrated only Ewing battery tests as an effective predictive factors. Our investigation found ACE genotype was not a risk factor in Cardiovascular Autonomic Neuropathy in the population of our study.