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4D printing: a cutting-edge platform for biomedical applications
journal contribution
posted on 2022-12-12, 02:13 authored by M Afzali Naniz, M Askari, Ali ZolfagharianAli Zolfagharian, M BodaghiNature’s materials have evolved over time to be able to respond to environmental stimuli by generating complex structures that can change their functions in response to distance, time, and direction of stimuli. A number of technical efforts are currently being made to improve printing resolution, shape fidelity, and printing speed to mimic the structural design of natural materials with three-dimensional printing. Unfortunately, this technology is limited by the fact that printed objects are static and cannot be reshaped dynamically in response to stimuli. In recent years, several smart materials have been developed that can undergo dynamic morphing in response to a stimulus, thus resolving this issue. Four-dimensional (4D) printing refers to a manufacturing process involving additive manufacturing, smart materials, and specific geometries. It has become an essential technology for biomedical engineering and has the potential to create a wide range of useful biomedical products. This paper will discuss the concept of 4D bioprinting and the recent developments in smart materials, which can be actuated by different stimuli and be exploited to develop biomimetic materials and structures, with significant implications for pharmaceutics and biomedical research, as well as prospects for the future.
History
Journal
Biomedical Materials (Bristol)Volume
17Article number
ARTN 062001Location
EnglandPublisher DOI
ISSN
1748-6041eISSN
1748-605XLanguage
EnglishPublication classification
C1 Refereed article in a scholarly journalIssue
6Publisher
IOP Publishing LtdUsage metrics
Categories
Keywords
Science & TechnologyTechnologyEngineering, BiomedicalMaterials Science, BiomaterialsEngineeringMaterials Science4D printingbiomedical applicationdrug deliverytissue engineeringmedical devicessoft roboticsSHAPE-MEMORY POLYMERTISSUESCAFFOLDSDELIVERYRELEASETECHNOLOGYTABLETSCHALLENGESHYDROGELSROBUSTBioengineeringBiomimetic MaterialsBioprintingPrinting, Three-DimensionalSmart MaterialsGeneric health relevanceBiomedical Engineering not elsewhere classifiedMedical Biotechnology not elsewhere classified
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