A structural comparison of inhibitor binding to PKB, PKA and PKA-PKB chimera

Davies, Thomas G; Verdonk, Marcel L; Graham, Brent; Saalau-Bethell, Susanne; Hamlett, Christopher CF; McHardy, Tatiana; Collins, Ian; Garrett, Michelle D; Workman, Paul; Woodhead, Steven J; Jhoti, Harren; Barford, David

A structural comparison of inhibitor binding to PKB, PKA and PKA-PKB chimera

journal contribution

posted on 2024-08-20, 05:47 authored by Thomas G Davies, Marcel L Verdonk, Brent Graham, Susanne Saalau-Bethell, Christopher CF Hamlett, Tatiana McHardy, Ian CollinsIan Collins, Michelle D Garrett, Paul Workman, Steven J Woodhead, Harren Jhoti, David Barford

A structural comparison of inhibitor binding to PKB, PKA and PKA-PKB chimera

History

Journal

JOURNAL OF MOLECULAR BIOLOGY

Volume

367

Pagination

882-894

Location

Netherlands

ISSN

0022-2836

eISSN

1089-8638

Language

English

Author URL

https://www.ncbi.nlm.nih.gov/pubmed/17275837

Publication classification

C1 Refereed article in a scholarly journal

Issue

3

Publisher

ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD

Publication URL

http://dx.doi.org/10.1016/j.jmb.2007.01.004

Usage metrics

Keywords

Science & Technology Life Sciences & Biomedicine Biochemistry & Molecular Biology kinase inhibitor structure-based drug design cancer Akt PROTEIN-KINASE-B SELECTIVE INHIBITORS CRYSTAL-STRUCTURES CATALYTIC SUBUNIT SIGNALING PATHWAY DRUG DESIGN AKT COMPLEX CANCER POTENT

A structural comparison of inhibitor binding to PKB, PKA and PKA-PKB chimera

History

Journal

Volume

Pagination

Location

ISSN

eISSN

Language

Author URL

Publication classification

Issue

Publisher

Publication URL

Usage metrics

Categories

Keywords

Licence

Exports