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A systematic review and meta-Analysis of exercise interventions in schizophrenia patients
journal contribution
posted on 2015-05-28, 00:00 authored by J Firth, J Cotter, R Elliott, P French, Alison YungAlison YungBackground The typically poor outcomes of schizophrenia could be improved through interventions that reduce cardiometabolic risk, negative symptoms and cognitive deficits; aspects of the illness which often go untreated. The present review and meta-Analysis aimed to establish the effectiveness of exercise for improving both physical and mental health outcomes in schizophrenia patients. Method We conducted a systematic literature search to identify all studies that examined the physical or mental effects of exercise interventions in non-Affective psychotic disorders. Of 1581 references, 20 eligible studies were identified. Data on study design, sample characteristics, outcomes and feasibility were extracted from all studies and systematically reviewed. Meta-Analyses were also conducted on the physical and mental health outcomes of randomized controlled trials. Results Exercise interventions had no significant effect on body mass index, but can improve physical fitness and other cardiometabolic risk factors. Psychiatric symptoms were significantly reduced by interventions using around 90 min of moderate-to-vigorous exercise per week (standardized mean difference: 0.72, 95% confidence interval-1.14 to-0.29). This amount of exercise was also reported to significantly improve functioning, co-morbid disorders and neurocognition. Conclusions Interventions that implement a sufficient dose of exercise, in supervised or group settings, can be feasible and effective interventions for schizophrenia.
History
Journal
Psychological MedicineVolume
45Issue
7Pagination
1343 - 1361Publisher DOI
ISSN
0033-2917eISSN
1469-8978Publication classification
C1 Refereed article in a scholarly journalUsage metrics
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No categories selectedKeywords
Social SciencesScience & TechnologyLife Sciences & BiomedicinePsychology, ClinicalPsychiatryPsychologyExercisefunctional recoveryphysical activitypsychotic disordersschizophreniaADD-ON TREATMENTLIFE-STYLE INTERVENTIONSINDUCED WEIGHT-GAINPHYSICAL-ACTIVITYNEGATIVE SYMPTOMSCARDIORESPIRATORY FITNESS1ST-EPISODE PSYCHOSISATYPICAL ANTIPSYCHOTICSAEROBIC EXERCISEEPISODE PATIENTS
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