A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry

Alt, K; Paterson, BM; Westein, E; Rudd, SE; Poniger, SS; Jagdale, S; Ardipradja, K; Connell, Tim; Krippner, GY; Nair, AKN; Wang, X; Tochon-Danguy, HJ; Donnelly, PS; Peter, K; Hagemeyer, CE

A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry

journal contribution

posted on 2024-06-04, 05:41 authored by K Alt, BM Paterson, E Westein, SE Rudd, SS Poniger, S Jagdale, K Ardipradja, Tim ConnellTim Connell, GY Krippner, AKN Nair, X Wang, HJ Tochon-Danguy, PS Donnelly, K Peter, CE Hagemeyer

A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry

History

Journal

Angewandte Chemie - International Edition

Volume

54

Pagination

7515-7519

Location

Germany

Publisher DOI

https://doi.org/10.1002/anie.201411507

ISSN

1433-7851

eISSN

1521-3773

Language

English

Publication classification

C1.1 Refereed article in a scholarly journal

Issue

26

Publisher

WILEY-V C H VERLAG GMBH

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Keywords

Science & Technology Physical Sciences Chemistry, Multidisciplinary Chemistry bioconjugation click chemistry fluorescence imaging PET imaging Sortase A SINGLE-CHAIN ANTIBODY ACTIVATED PLATELETS THERAPEUTIC INDEX TERMINAL ALKYNES AMINO-ACIDS IN-VITRO SORTASE CONJUGATION GPIIB/IIIA PROTEINS

A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry

History

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Volume

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Location

Publisher DOI

ISSN

eISSN

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Publisher

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