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AarF domain containing kinase 3 (ADCK3) mutant cells display signs of oxidative stress, defects in mitochondrial homeostasis and lysosomal accumulation
journal contribution
posted on 2016-02-01, 00:00 authored by J K Cullen, N A Murad, A Yeo, Matthew McKenzieMatthew McKenzie, M Ward, K L Chong, N L Schieber, R G Parton, Y C Lim, E Wolvetang, G J Maghzal, R Stocker, M F LavinAarF domain containing kinase 3 (ADCK3) mutant cells display signs of oxidative stress, defects in mitochondrial homeostasis and lysosomal accumulation
History
Journal
PLoS ONEVolume
11Issue
2Article number
ARTN e0148213Publisher
PUBLIC LIBRARY SCIENCELocation
United StatesPublisher DOI
Link to full text
ISSN
1932-6203eISSN
1932-6203Language
EnglishPublication classification
C Journal article; C1.1 Refereed article in a scholarly journalCopyright notice
2016, Cullen et al.Usage metrics
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Categories
Keywords
Science & TechnologyMultidisciplinary SciencesScience & Technology - Other TopicsCOENZYME Q(10) DEFICIENCYSACCHAROMYCES-CEREVISIAEUBIQUINONE BIOSYNTHESISCAENORHABDITIS-ELEGANSCOQ(10) DEFICIENCYCEREBELLAR-ATAXIARAT-LIVERLIFE-SPANCOMPLEXMUTATIONSCell SurvivalCytosolDNA DamageEndopeptidase KGene Expression RegulationGlutathione TransferaseHeLa CellsHomeostasisHumansLentivirusLysosomesMembrane Potential, MitochondrialMitochondriaMitochondrial ProteinsMutagenesis, Site-DirectedMutationOxidative PhosphorylationOxidative StressProtein Structure, TertiaryRNA InterferenceReactive Oxygen SpeciesRecombinant Fusion ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsUbiquinone