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Advancements in magnetic aptasensors: Recent progress and future trends in biosensor technology

journal contribution
posted on 2024-03-07, 22:40 authored by MB Behyar, Azadeh NilghazAzadeh Nilghaz, R Ebrahimi, M Hasanzadeh, N Shadjou
Biosensors have been explored for their application in analytical assays with an increasing reliance on nanomaterials and biomolecule recognition units. Recently, magnetic nanoparticle-aptamer (MNPA) hybrids found crucial for their strengths in target binding, low limit of detection (LOD), enhanced sensitivity, exceptional stability, and superior selectivity. They have been employed for the identification of a diverse range of analytes in biological, food, and environmental samples. However, their integration with conventional sensing technologies remains a challenge. Herein, the current state-of-the-art of MNPA sensors are reviewed. First, the significance of using MNP and aptamers in biosensors is discussed and then the technologies incorporating MNPAs to achieve higher sensitivity and selectivity in quantifying analytical samples are introduced. Finally, prospects and practical approaches to address the existing drawbacks of MNPA sensors are presented.

History

Journal

TrAC - Trends in Analytical Chemistry

Volume

172

Article number

117549

Pagination

117549-117549

ISSN

0165-9936

eISSN

1879-3142

Language

en

Publisher

Elsevier BV

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