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Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide

journal contribution
posted on 2007-09-01, 00:00 authored by S L Khaw, P A Downie, K D Waters, David Ashley, J A Heath
Mesna is widely used for the prevention of cyclophosphamide-related hemorrhagic cystitis. It has been associated with hypersensitivity-like cutaneous and systemic reactions in adult patients. We report a series of children with malignant disease, who developed such reactions following mesna administration and discuss possible mechanisms and management issues.

History

Journal

Pediatric blood & cancer

Volume

49

Issue

3

Pagination

341 - 343

Publisher

John Wiley & Sons

Location

Hoboken, N.J.

ISSN

1545-5009

eISSN

1545-5017

Language

eng

Publication classification

C2.1 Other contribution to refereed journal

Copyright notice

2005, Wiley-Liss

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