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Aflatoxins in Cereals and Cereal-Based Products: Occurrence, Toxicity, Impact on Human Health, and Their Detoxification and Management Strategies

journal contribution
posted on 2023-02-07, 01:43 authored by P Kumar, A Gupta, Dipendra Mahato, S Pandhi, AK Pandey, R Kargwal, S Mishra, R Suhag, N Sharma, V Saurabh, V Paul, M Kumar, R Selvakumar, Shirani GamlathShirani Gamlath, M Kamle, HAE Enshasy, JA Mokhtar, S Harakeh
Cereals and cereal-based products are primary sources of nutrition across the world. However, contamination of these foods with aflatoxins (AFs), secondary metabolites produced by several fungal species, has raised serious concerns. AF generation in innate substrates is influenced by several parameters, including the substrate type, fungus species, moisture content, minerals, humidity, temperature, and physical injury to the kernels. Consumption of AF-contaminated cereals and cereal-based products can lead to both acute and chronic health issues related to physical and mental maturity, reproduction, and the nervous system. Therefore, the precise detection methods, detoxification, and management strategies of AFs in cereal and cereal-based products are crucial for food safety as well as consumer health. Hence, this review provides a brief overview of the occurrence, chemical characteristics, biosynthetic processes, health hazards, and detection techniques of AFs, along with a focus on detoxification and management strategies that could be implemented for food safety and security.

History

Journal

Toxins

Volume

14

Article number

ARTN 687

Location

Switzerland

ISSN

2072-6651

eISSN

2072-6651

Language

English

Publication classification

C1 Refereed article in a scholarly journal

Issue

10

Publisher

MDPI