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Among vitamin B12 deficient older people, high folate levels are associated with worse cognitive function: combined data from three cohorts
journal contribution
posted on 2014-01-01, 00:00 authored by Eileen Moore, D Ames, Alastair Mander, Ross CarneRoss Carne, H Brodaty, M C Woodward, K Boundy, K A Ellis, A I Bush, N G Faux, R N Martins, C L Masters, C C Rowe, C Szoeke, David WattersDavid WattersFolate fortification of food aims to reduce the number of babies born with neural tube defects, but has been associated with cognitive impairment when vitamin B12 levels are deficient. Given the prevalence of low vitamin B12 levels among the elderly, and the global deployment of food fortification programs, investigation of the associations between cognitive impairment, vitamin B12, and folate are needed.
History
Journal
Journal of alzheimer's diseaseVolume
39Issue
3Pagination
661 - 668Publisher
IOS PressLocation
Amsterdam, The NetherlandsPublisher DOI
eISSN
1875-8908Language
engPublication classification
C Journal article; C1 Refereed article in a scholarly journalCopyright notice
2014, IOS PressUsage metrics
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No categories selectedKeywords
AgedAlzheimer's diseasecognitionfolic acidvitamin B12Aged, 80 and overAgingAustraliaCognition DisordersCohort StudiesFemaleHumansMaleMental Status ScheduleVitamin B 12 DeficiencyScience & TechnologyLife Sciences & BiomedicineNeurosciencesNeurosciences & NeurologyBASE-LINE CHARACTERISTICSFOLIC-ACIDALZHEIMERS-DISEASESERUM FOLATEHOMOCYSTEINEPOPULATIONFORTIFICATIONIMPAIRMENTDECLINE
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