Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress
Version 2 2024-06-05, 08:09Version 2 2024-06-05, 08:09
Version 1 2020-05-15, 15:04Version 1 2020-05-15, 15:04
journal contribution
posted on 2024-06-05, 08:09 authored by Mark Halloran, Audrey MG Ragagnin, Marta Vidal, Sonam Parakh, Shu Yang, Benjamin Heng, Natalie Grima, Hamideh Shahheydari, Kai-Ying Soo, Ian Blair, Gilles J Guillemin, Vinod SundaramoorthyVinod Sundaramoorthy, Julie D AtkinAmyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress
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Journal
CELLULAR AND MOLECULAR LIFE SCIENCESVolume
77Pagination
3859-3873Location
SwitzerlandPublisher DOI
ISSN
1420-682XeISSN
1420-9071Language
EnglishPublication classification
C1 Refereed article in a scholarly journalIssue
19Publisher
SPRINGER BASEL AGUsage metrics
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Keywords
Science & TechnologyLife Sciences & BiomedicineBiochemistry & Molecular BiologyCell BiologyAmyotrophic lateral sclerosisER-Golgi traffickingER stressUbiquilin-2Unfolded protein responseGolgi fragmentationUNFOLDED PROTEIN RESPONSEMOTOR-NEURON DEATHSUPEROXIDE-DISMUTASERETROGRADE TRANSPORTCELLULAR TRAFFICKINGSPINAL-CORDALSAGGREGATIONSOD1DEGRADATION3101 Biochemistry and cell biology3202 Clinical sciences
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