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Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress
journal contribution
posted on 2020-10-01, 00:00 authored by Mark Halloran, Audrey M G Ragagnin, Marta Vidal, Sonam Parakh, Shu Yang, Benjamin Heng, Natalie Grima, Hamideh Shahheydari, Kai-Ying Soo, Ian Blair, Gilles J Guillemin, Vinod SundaramoorthyVinod Sundaramoorthy, Julie D AtkinAmyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress
History
Journal
Cellular and Molecular Life SciencesVolume
77Issue
19Pagination
3859 - 3873Publisher
SpringerLocation
Berlin, GermanyPublisher DOI
ISSN
1420-682XeISSN
1420-9071Language
engPublication classification
C1 Refereed article in a scholarly journalUsage metrics
Keywords
AGGREGATIONALSAmyotrophic lateral sclerosisBiochemistry & Molecular BiologyCell BiologyCELLULAR TRAFFICKINGDEGRADATIONER stressER-Golgi traffickingGolgi fragmentationLife Sciences & BiomedicineMOTOR-NEURON DEATHRETROGRADE TRANSPORTScience & TechnologySOD1SPINAL-CORDSUPEROXIDE-DISMUTASEUbiquilin-2Unfolded protein responsePhysiology
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