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Anesthetic induction for ECT with etomidate is associated with longer seizure duration than thiopentone.
journal contributionposted on 1998-06-01, 00:00 authored by S Saffer, Michael BerkMichael Berk
Many factors influence seizure duration associated with electroconvulsive therapy (ECT). This is a chart review study to assess seizure duration measured with both electroencephalography and electromyography after anesthetic induction with either thiopentone or etomidate. Thirty-seven patients receiving ECT for depression were entered into the study, and a pair of seizures was measured from each patient. Alternate induction agents were used in sequential pairings, and the study was controlled for interval between seizures, laterality, and percent energy. Etomidate was associated with a significantly (p = 0.0002, F = 15.84, df = 1, analysis of variance) longer seizure duration (mean = 34.43 s, SD = 16.06) than thiopentone (mean = 21.73 s, SD = 9.33).
JournalThe Journal of Electroconvulsive Therapy
Pagination89 - 93
PublisherLippincott, Williams & Wilkins
Publication classificationC1.1 Refereed article in a scholarly journal
Copyright notice1998, Lippincott, Williams & Wilkins
CategoriesNo categories selected
AdolescentAdultAgedAnesthesiaAnesthetics, IntravenousDepressive Disorder, MajorElectroconvulsive TherapyEtomidateFemaleHumansMaleMental DisordersMiddle AgedReaction TimeThiopentalScience & TechnologyLife Sciences & BiomedicineBehavioral SciencesPsychiatryseizure duration, after anesthetic inductionthiopentoneUNILATERAL ELECTROCONVULSIVE-THERAPYPROPOFOLEFFICACYAGENTS