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Anesthetic induction for ECT with etomidate is associated with longer seizure duration than thiopentone.
Many factors influence seizure duration associated with electroconvulsive therapy (ECT). This is a chart review study to assess seizure duration measured with both electroencephalography and electromyography after anesthetic induction with either thiopentone or etomidate. Thirty-seven patients receiving ECT for depression were entered into the study, and a pair of seizures was measured from each patient. Alternate induction agents were used in sequential pairings, and the study was controlled for interval between seizures, laterality, and percent energy. Etomidate was associated with a significantly (p = 0.0002, F = 15.84, df = 1, analysis of variance) longer seizure duration (mean = 34.43 s, SD = 16.06) than thiopentone (mean = 21.73 s, SD = 9.33).
History
Journal
The Journal of Electroconvulsive TherapyVolume
14Issue
2Pagination
89 - 93Publisher
Lippincott, Williams & WilkinsLocation
UNITED STATESISSN
1533-4112Language
engPublication classification
C1.1 Refereed article in a scholarly journalCopyright notice
1998, Lippincott, Williams & WilkinsUsage metrics
Categories
No categories selectedKeywords
AdolescentAdultAgedAnesthesiaAnesthetics, IntravenousDepressive Disorder, MajorElectroconvulsive TherapyEtomidateFemaleHumansMaleMental DisordersMiddle AgedReaction TimeThiopentalScience & TechnologyLife Sciences & BiomedicineBehavioral SciencesPsychiatryseizure duration, after anesthetic inductionthiopentoneUNILATERAL ELECTROCONVULSIVE-THERAPYPROPOFOLEFFICACYAGENTS