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Anti-Angiogenic Properties of Ginsenoside Rg3

Version 3 2024-06-19, 06:44
Version 2 2024-06-13, 01:42
Version 1 2021-11-22, 10:34
journal contribution
posted on 2024-06-19, 06:44 authored by M Nakhjavani, E Smith, AR Townsend, TJ Price, JE Hardingham
Ginsenoside Rg3 (Rg3) is a member of the ginsenoside family of chemicals extracted from Panax ginseng. Like other ginsenosides, Rg3 has two epimers: 20(S)-ginsenoside Rg3 (SRg3) and 20(R)-ginsenoside Rg3 (RRg3). Rg3 is an intriguing molecule due to its anti-cancer properties. One facet of the anti-cancer properties of Rg3 is the anti-angiogenic action. This review describes the controversies on the effects and effective dose range of Rg3, summarizes the evidence on the efficacy of Rg3 on angiogenesis, and raises the possibility that Rg3 is a prodrug.

History

Journal

Molecules (Basel, Switzerland)

Volume

25

Article number

ARTN 4905

Pagination

1 - 18

Location

Switzerland

ISSN

1420-3049

eISSN

1420-3049

Language

English

Publication classification

C1 Refereed article in a scholarly journal

Issue

21

Publisher

MDPI