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At a glance: cellular biology for engineers
journal contribution
posted on 2008-10-01, 00:00 authored by Khashayar Khoshmanesh, Abbas KouzaniAbbas Kouzani, Saeid Nahavandi, Sara Baratchi, Jagat KanwarEngineering contributions have played an important role in the rise and evolution of cellular biology. Engineering technologies have helped biologists to explore the living organisms at cellular and molecular levels, and have created new opportunities to tackle the unsolved biological problems. There is now a growing demand to further expand the role of engineering in cellular biology research. For an engineer to play an effective role in cellular biology, the first essential step is to understand the cells and their components. However, the stumbling block of this step is to comprehend the information given in the cellular biology literature because it best suits the readers with a biological background. This paper aims to overcome this bottleneck by describing the human cell components as micro-plants that form cells as micro-bio-factories. This concept can accelerate the engineers’ comprehension of the subject. In this paper, first the structure and function of different cell components are described. In addition, the engineering attempts to mimic various cell components through numerical modelling or physical implementation are highlighted. Next, the interaction of different cell components that facilitate complicated chemical processes, such as energy generation and protein synthesis, are described. These complex interactions are translated into simple flow diagrams, generally used by engineers to represent multi-component processes.
History
Journal
Computational biology and chemistryVolume
32Issue
5Pagination
315 - 331Publisher
ElsevierLocation
Oxford, EnglandPublisher DOI
ISSN
1476-9271eISSN
1476-928XLanguage
engPublication classification
C1 Refereed article in a scholarly journalCopyright notice
2008, ElsevierUsage metrics
Categories
No categories selectedKeywords
cellular biologycell organellesmicro-bio-factoryenergy generationprotein synthesisScience & TechnologyLife Sciences & BiomedicineTechnologyBiologyComputer Science, Interdisciplinary ApplicationsLife Sciences & Biomedicine - Other TopicsComputer ScienceTRANSCRIPTION REGULATORY NETWORKSENDOPLASMIC-RETICULUMGOLGI-APPARATUSBIOFUEL CELLPLASMA-MEMBRANEMITOCHONDRIAL-DNAMOLECULAR-BIOLOGYSTRUCTURAL BASISMESSENGER-RNACANCER