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Baseline comorbidities in a population-bases cohort of rheumatoid arthritis patients receiving biological therapy: data from the Australian Rheumatology Association database

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journal contribution
posted on 2024-06-17, 06:57 authored by A Briggs, L March, M Lassere, C Reid, L Henderson, B Murphy, R Van Den Haak, A Rischin, M Staples, R Buchbinder
Aims: To describe the baseline characteristics of an Australian population-based cohort of rheumatoid arthritis (RA) patients commencing biological therapy.

Methods
: Descriptive analysis from the Australian Rheumatology Association Database (ARAD).

Results
: Up to October 2006, there were 681 RA patients taking biologics enrolled in ARAD. Baseline data were available for 624 (72% female, mean (SD) age 57.0 (12.5) years). Of these, 59.5% reported at least one comorbid condition, most commonly hypertension (35.7%) and osteoporosis (30.4%); 61 (9.8%) had a history of malignancy (35 nonmelanoma skin, 5 breast, 4 bowel, 5 cervix, 3 melanoma, 3 prostate and 1 each of lip, lung, myeloma, testis, uterus, vagina). Self-reported infections within the previous 6 months were common (71.5%).

Conclusions
: History of comorbidities, including recent infections, is common among Australian RA patients commencing biologics, and 10% have a history of malignancy. This may impact future evaluations of health outcomes among this population, including attribution of adverse events of biologic therapy.

History

Journal

International journal of rheumatology

Volume

2009

Article number

861481

Pagination

1-8

Location

New York, N.Y.

Open access

  • Yes

ISSN

1687-9260

eISSN

1687-9279

Language

eng

Publication classification

C1 Refereed article in a scholarly journal

Copyright notice

2009, The Authors

Publisher

Hindawi Publishing Corporation

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