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Bat cells from Pteropus alecto are susceptible to influenza A virus infection and reassortment

journal contribution
posted on 2013-11-01, 00:00 authored by Daniel Dlugolenski, L Jones, S M Tompkins, G Crameri, L-F Wang, R A Tripp
Waterfowl are primary hosts for influenza A viruses (IAVs); however, there is sporadic infection of swine and other species that pose a risk of zoonotic spread. Yellow-shouldered bats were shown to be hosts of an IAV, thereby constituting a potential novel reservoir. We show that Pteropus alecto kidney cells (PaKi) are susceptible to infection and sustain replication of A/WSN/33 (H1N1) and A/Vietnam/1203/04 (H5N1). Importantly, we show that co-infection of PaKi cells results in novel reassortants.

History

Journal

Influenza and other respiratory viruses

Volume

7

Issue

6

Pagination

900 - 903

Publisher

Wiley

Location

London, Eng.

eISSN

1750-2659

Language

eng

Publication classification

C Journal article; C1.1 Refereed article in a scholarly journal

Copyright notice

2013, John Wiley & Sons Ltd

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