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Biocompatibility of boron nitride nanosheets

journal contribution
posted on 01.01.2018, 00:00 authored by Srikanth Mateti, Cynthia Wong, Zhen Liu, Wenrong YangWenrong Yang, Y Li, Luhua LiLuhua Li, Ying (Ian) ChenYing (Ian) Chen
The properties and applications of boron nitride (BN) nanosheets are complementary to those of graphene, with advantages in chemical and thermal stability. Biocompatibility is an important property for future biomedical applications but has not been investigated experimentally. We studied the biocompatibility of BN nanosheets of different sizes and compared it with that of BN nanoparticles in osteoblast-like cells (SaOS 2). Our results showed that the biocompatibility of BN nanomaterials depends on their size, shape, structure, and surface chemical properties. Electron spin resonance measurement revealed that unsaturated B atoms located at the nanosheet edges or on the particle surface are responsible for the cell death.

History

Journal

Nano research

Volume

11

Issue

1

Pagination

334 - 342

Publisher

Tsinghua University Press

Location

Beijing, China

ISSN

1998-0124

eISSN

1998-0000

Language

eng

Publication classification

C Journal article; C1 Refereed article in a scholarly journal

Copyright notice

2017, Tsinghua University Press and Springer-Verlag Berlin Heidelberg