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Biocompatibility of boron nitride nanosheets
journal contribution
posted on 2018-01-01, 00:00 authored by Srikanth Mateti, Cynthia Wong, Zhen Liu, Wenrong YangWenrong Yang, Y Li, Luhua LiLuhua Li, Ying (Ian) ChenYing (Ian) ChenThe properties and applications of boron nitride (BN) nanosheets are complementary to those of graphene, with advantages in chemical and thermal stability. Biocompatibility is an important property for future biomedical applications but has not been investigated experimentally. We studied the biocompatibility of BN nanosheets of different sizes and compared it with that of BN nanoparticles in osteoblast-like cells (SaOS 2). Our results showed that the biocompatibility of BN nanomaterials depends on their size, shape, structure, and surface chemical properties. Electron spin resonance measurement revealed that unsaturated B atoms located at the nanosheet edges or on the particle surface are responsible for the cell death.
History
Journal
Nano researchVolume
11Issue
1Pagination
334 - 342Publisher
Tsinghua University PressLocation
Beijing, ChinaPublisher DOI
ISSN
1998-0124eISSN
1998-0000Language
engPublication classification
C Journal article; C1 Refereed article in a scholarly journalCopyright notice
2017, Tsinghua University Press and Springer-Verlag Berlin HeidelbergUsage metrics
Categories
No categories selectedKeywords
boron nitridenanosheetbiocompatibilityScience & TechnologyPhysical SciencesTechnologyChemistry, PhysicalNanoscience & NanotechnologyMaterials Science, MultidisciplinaryPhysics, AppliedChemistryScience & Technology - Other TopicsMaterials SciencePhysicsCARBON NANOTUBESDRUG-DELIVERYIN-VITROGRAPHENECELLSSIZEWS2NANOPARTICLESCYTOTOXICITYCOMPOSITES