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Cancer is not (only) a senescence problem
journal contribution
posted on 2018-03-01, 00:00 authored by F Thomas, F Vavre, T Tissot, M Vittecoq, M Giraudeau, F Bernex, D Misse, F Renaud, Nynke RavenNynke Raven, Christa BeckmannChrista Beckmann, R Hamede, Peter BiroPeter Biro, Beata UjvariBeata UjvariAge is one of the strongest predictors of cancer and risk of death from cancer. Cancer is therefore generally viewed as a senescence-related malady. However, cancer also exists at subclinical levels in humans and other animals, but its earlier effects on the body are poorly known by comparison. We argue here that cancer is a significant but ignored burden on the body and is likely to be a strong selective force from early during the lifetime of an organism. It is time to adopt this novel view of malignant pathologies to improve our understanding of the ways in which oncogenic phenomena influence the ecology and evolution of animals long before their negative impacts become evident and fatal.
History
Journal
Trends in cancerVolume
4Issue
3Pagination
169 - 172Publisher
ElsevierLocation
Amsterdam, The NetherlandsPublisher DOI
eISSN
2405-8025Language
engPublication classification
C Journal article; C1 Refereed article in a scholarly journalCopyright notice
2018, Elsevier Inc.Usage metrics
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