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Cardiovascular disease risk in the offspring of diabetic women: the impact of the intrauterine environment

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journal contribution
posted on 2012-10-01, 00:00 authored by L Marco, Kate MccloskeyKate Mccloskey, Peter VuillerminPeter Vuillermin, D Burgner, J Said, A L Ponsonby
The incidence of gestational diabetes is increasing worldwide, exposing large numbers of infants to hyperglycaemia whilst in utero. This exposure may have a long-term negative impact on the cardiovascular health of the offspring. Novel methods to assess cardiovascular status in the neonatal period are now available—including measuring arterial intima-media thickness and retinal photography. These measures will allow researchers to assess the relative impact of intrauterine exposures, distinguishing these from genetic or postnatal environmental factors. Understanding the long-term impact of the intrauterine environment should allow the development of more effective health policy and interventions to decrease the future burden of cardiovascular disease. Initiating disease prevention aimed at the developing fetus during the antenatal period may optimise community health outcomes.

History

Journal

Experimental diabetes research

Volume

2012

Article number

565160

Pagination

1 - 10

Publisher

Hindawi Publishing Corporation

Location

New York, NY

ISSN

1687-5303

eISSN

1687-5214

Language

eng

Publication classification

C1.1 Refereed article in a scholarly journal

Copyright notice

2012, The Authors