vuillermin-cardiovasculardisease-2013.pdf (294.42 kB)
Cardiovascular disease risk in the offspring of diabetic women: the impact of the intrauterine environment
journal contribution
posted on 2012-10-01, 00:00 authored by L Marco, Kate MccloskeyKate Mccloskey, Peter VuillerminPeter Vuillermin, D Burgner, J Said, A L PonsonbyThe incidence of gestational diabetes is increasing worldwide, exposing large numbers of infants to hyperglycaemia whilst in utero. This exposure may have a long-term negative impact on the cardiovascular health of the offspring. Novel methods to assess cardiovascular status in the neonatal period are now available—including measuring arterial intima-media thickness and retinal photography. These measures will allow researchers to assess the relative impact of intrauterine exposures, distinguishing these from genetic or postnatal environmental factors. Understanding the long-term impact of the intrauterine environment should allow the development of more effective health policy and interventions to decrease the future burden of cardiovascular disease. Initiating disease prevention aimed at the developing fetus during the antenatal period may optimise community health outcomes.
History
Journal
Experimental diabetes researchVolume
2012Article number
565160Pagination
1 - 10Publisher
Hindawi Publishing CorporationLocation
New York, NYPublisher DOI
ISSN
1687-5303eISSN
1687-5214Language
engPublication classification
C1.1 Refereed article in a scholarly journalCopyright notice
2012, The AuthorsUsage metrics
Categories
No categories selectedKeywords
gestational diabeteshyperglycaemiacardiovascular healthcardiovascular status in the neonatal periodScience & TechnologyLife Sciences & BiomedicineEndocrinology & MetabolismMedicine, Research & ExperimentalResearch & Experimental MedicineINTIMA-MEDIA THICKNESSMETABOLIC SYNDROMEFAMILIAL HYPERCHOLESTEROLEMIAMATERNAL OBESITYNEUROPEPTIDE-YLIPID PROFILEHEART-DISEASEATHEROSCLEROSISCHILDRENINSULIN
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC