A two-level multi-variable design of experiment (DoE) approach was used to investigate the influence and interaction of lubricant type, die surface finish, contact pressure, sheet metal coating and draw speed on friction. For this DoE, the flat face friction test (FFF) and the draw bead simulator (DBS) were used to measure the coefficient of friction. The experiments were run in random order with at least three replicates. The Yates algorithm was employed to determine the significance of the main effects and their interactions. It was found that the Zincanneal coating lowers friction and reduces variation within a specific test condition. The DBS results illustrated an insensitivity of the variables investigated to the friction coefficient. However, the rough DBS die was sensitive to blank coating. The polished surface of the FFF test illustrated a similar insensitivity.