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Chemiluminescence detection of opium poppy (papaver somniferum) alkaloids
journal contribution
posted on 2008-11-04, 00:00 authored by Paul FrancisPaul Francis, Jacqui AdcockJacqui Adcock, Jason Wesley Costin, Stuart Purcell, Fred PfefferFred Pfeffer, Neil BarnettNeil BarnettA review with 98 references. The determination of the opium poppy (Papaver somniferum) alkaloids and their semi-synthetic derivatives has important applications in industrial process monitoring, clinical analysis and forensic science. Liquid-phase chemiluminescence reagents such as tris(2,2′-bipyridyl)ruthenium(II) and acidic potassium permanganate exhibit remarkable sensitivity and complementary selectivity for many P. somniferum alkaloids, which has been exploited in the development of a range of analytical procedures using flow analysis, high-performance liquid chromatography, capillary electrophoresis and microfluidic instrumentation.
History
Journal
Journal of pharmaceutical and biomedical analysisVolume
48Issue
3Pagination
508 - 518Publisher
Elsevier B.V.Location
NetherlandsPublisher DOI
ISSN
0731-7085eISSN
1873-264XLanguage
engPublication classification
C1 Refereed article in a scholarly journalCopyright notice
2008, Elsevier B.V.Usage metrics
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chemiluminescence detectionprocess analytical chemistrymorphinecodeineheroinoxycodoneflow injection analysissequential injection analysishigh-performance liquid chromatographyScience & TechnologyPhysical SciencesLife Sciences & BiomedicineChemistry, AnalyticalPharmacology & PharmacyChemistryFLOW-INJECTION ANALYSISACIDIC POTASSIUM-PERMANGANATEIN-PROCESS STREAMSPERFORMANCE LIQUID-CHROMATOGRAPHYMONOLITHIC COLUMN CHROMATOGRAPHYCAPILLARY-ELECTROPHORESISTRIS(2,2'-BIPYRIDYL)RUTHENIUM(II) CHEMILUMINESCENCEELECTROGENERATED CHEMILUMINESCENCEPHARMACEUTICAL FORMULATIONSSENSITIVE DETERMINATION
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