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Colorimetric and fluorescent anion sensors : an overview of recent developments in the use of 1,8-naphthalimide-based chemosensors

journal contribution
posted on 2010-01-01, 00:00 authored by R Duke, E Veale, Fred PfefferFred Pfeffer, P Kruger, T Gunnlaugsson
This critical review focuses on the development of anion sensors, being either fluorescent and/or colorimetric, based on the use of the 1,8-naphthalimide structure; a highly versatile building unit that absorbs and emits at long wavelengths. The review commences with a short description of the most commonly used design principles employed in chemosensors, followed by a discussion on the photophysical properties of the 4-amino-1,8-naphthalimide structure which has been most commonly employed in both cation and anion sensing to date. This is followed by a review of the current state of the art in naphthalimide-based anion sensing, where systems using ureas, thioureas and amides as hydrogen-bonding receptors, as well as charged receptors have been used for anion sensing in both organic and aqueous solutions, or within various polymeric networks, such as hydrogels. The review concludes with some current and future perspectives including the use of the naphthalimides for sensing small biomolecules, such as amino acids, as well as probes for incorporation and binding to proteins; and for the recognition/sensing of polyanions such as DNA, and their potential use as novel therapeutic and diagnostic agents (95 references).

History

Journal

Chemical society reviews

Volume

39

Issue

10

Season

Supramolecular chemistry of anionic species themed issue

Pagination

3936 - 3953

Publisher

Royal Society of Chemistry

Location

Cambridge, England

ISSN

0306-0012

eISSN

1460-4744

Language

eng

Publication classification

C1 Refereed article in a scholarly journal

Copyright notice

2010, The Royal Society of Chemistry