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Comparison of pulse rate variability with heart rate variability during obstructive sleep apnea
journal contribution
posted on 2011-03-01, 00:00 authored by A H Khandoker, Chandan KarmakarChandan Karmakar, M PalaniswamiWe investigate whether pulse rate variability (PRV) extracted from finger photo-plethysmography (Pleth) waveforms can be the substitute of heart rate variability (HRV) from RR intervals of ECG signals during obstructive sleep apnea (OSA). Simultaneous measurements (ECG and Pleth) were taken from 29 healthy subjects during normal (undisturbed sleep) breathing and 22 patients with OSA during OSA events. Highly significant (p<0.01) correlations (1.0>r>0.95) were found between heart rate (HR) and pulse rate (PR). Bland-Altman plot of HR and PR shows good agreement (<5% difference). Comparison of 2 min recording epochs demonstrated significant differences (p<0.01) in time, frequency domains and complexity analysis, between normal and OSA events using PRV as well as HRV measures. Results suggest that both HRV and PRV indices could be used to distinguish OSA events from normal breathing during sleep. However, several variability measures (SDNN, RMSSD, HF power, LF/HF and sample entropy) of PR and HR were found to be significantly (p<0.01) different during OSA events. Therefore, we conclude that PRV provides accurate inter-pulse variability to measure heart rate variability under normal breathing in sleep but does not precisely reflect HRV in sleep disordered breathing.
History
Journal
Medical engineering & physicsVolume
33Issue
2Pagination
204 - 209Publisher
ElsevierLocation
Amsterdam, The NetherlandsPublisher DOI
eISSN
1873-4030Language
engPublication classification
C Journal article; C1.1 Refereed article in a scholarly journalCopyright notice
2010, IPEM. Published by Elsevier Ltd. All rights reserved.Usage metrics
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AdultAgedAlgorithmsCardiovascular Physiological PhenomenaElectrocardiographyEntropyHeart RateHumansMiddle AgedPhotoplethysmographyPulseRespirationSleepSleep Apnea SyndromesSleep Apnea, ObstructiveScience & TechnologyTechnologyEngineering, BiomedicalEngineeringPulse rateSleep apneaHeart rate variabilityAPPROXIMATE ENTROPY
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