austin-computerisedmemory-2019.pdf (415.31 kB)
Computerised memory specificity training (c-MeST) for the treatment of major depression: a study protocol for a randomised controlled trial
journal contribution
posted on 2019-02-27, 00:00 authored by David HallfordDavid Hallford, David AustinDavid Austin, Filip Raes, Keisuke TakanoINTRODUCTION: Major depression is a prevalent and debilitating disorder, but many sufferers do not receive support or respond to current treatments. The development of easily accessible and low-intensity treatments that have clear cognitive mechanisms of change is indicated. Memory specificity training (MeST) is an intervention for depression that targets deficits in recalling detailed memories of past experiences through repeated practice of autobiographical memory retrieval. This randomised controlled trial will assess the efficacy of an online, computerised version of MeST (c-MeST). METHODS AND ANALYSIS: Adults aged 18 and over with a current major depressive episode (MDE) will be recruited and randomised to have access to the seven session, online c-MeST programme for 2 weeks, or to a wait-list control group. The primary outcomes will be diagnostic status of MDE and self-reported depressive symptoms at postintervention. One-month and three-month follow-ups will be collected. Increases in autobiographical memory specificity will be assessed as a mediator of change, as well as other variables thought to contribute to reduced memory specificity, such as rumination and cognitive avoidance. ETHICS AND DISSEMINATION: Ethics approval has been granted by the Deakin University Human Research Ethics Committee to conduct the study (ID: 2017_168). The findings will be disseminated through scholarly publications and workshops and will inform future trials, such as with an active comparator or as an adjunct treatment. TRIAL REGISTRATION NUMBER: ACTRN12618000257268; Pre-results.
History
Journal
BMJ openVolume
9Issue
2Article number
e024508Pagination
1 - 6Publisher
BMJ Publishing GroupLocation
London, Eng.Publisher DOI
Link to full text
eISSN
2044-6055Language
engPublication classification
C1 Refereed article in a scholarly journalCopyright notice
2019, Author(s) (or their employer(s))Usage metrics
Categories
No categories selectedKeywords
autobiographical memory specificitydepressionmemory specificity trainingstudy protocolScience & TechnologyLife Sciences & BiomedicineMedicine, General & InternalGeneral & Internal MedicineAUTOBIOGRAPHICAL MEMORYMENTAL-HEALTHNATIONAL-SURVEYVALIDATIONMETAANALYSISRELIABILITYRUMINATIONDISORDERSEFFICACYPROGRAM
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC