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Corpus callosum size and shape alterations in adolescent inhalant users
journal contribution
posted on 2013-09-01, 00:00 authored by M Takagi, D I Lubman, M Walterfang, S Barton, D Reutens, Amanda WoodAmanda Wood, M YücelInhalants, frequently abused during adolescence, are neurotoxic to white matter. We investigated the impact of inhalant misuse on the morphology of the corpus callosum (CC), the largest white matter bundle in the brain, in an adolescent sample of inhalant users [n = 14; mean age = 17.3; standard deviation (SD) = 1.7], cannabis users (n = 11; mean age = 19.7; SD = 1.7) and community controls (n = 9; mean age = 19.5; SD = 2.6). We identified significant morphological differences in the CC among inhalant users compared with community controls. There were no morphological differences between inhalant and cannabis users. Our findings may represent the early stages of neurobiological damage associated with chronic inhalant misuse.
History
Journal
Addiction biologyVolume
18Issue
5Pagination
851 - 854Publisher
John Wiley & SonsLocation
Chichester, Eng.Publisher DOI
ISSN
1355-6215eISSN
1369-1600Language
engPublication classification
C1 Refereed article in a scholarly journalCopyright notice
2011, The AuthorsUsage metrics
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