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Cost-effective three-dimensional printing of visibly transparent microchips within minutes
journal contribution
posted on 2014-03-18, 00:00 authored by A I Shallan, P Smejkal, M Corban, Rosanne GuijtRosanne Guijt, M C BreadmoreOne-step fabrication of transparent three dimensional (3D) microfluidic to millifluidic devices was demonstrated using a commercial 3D printer costing $2300 with 500 mL of clear resin for $138. It employs dynamic mask projection stereolithography, allowing fast concept-to-chip time. The fully automated system allows fabrication of models of up to 43 mm × 27 mm × 180 mm (x × y × z) at printing speeds of 20 mm/h in height regardless of the design complexity. The minimal cross sectional area of 250 μm was achieved for monolithic microchannels and 200 μm for
positive structures (templates for soft lithography). The colorless resin’s good light transmittance (>60% transmission at wavelengths of >430 nm) allows for on-chip optical detection, while the electrically insulating material allows electrophoretic separations. To demonstrate its applicability in microfluidics, the printer was used for the fabrication of a micromixer, a gradient generator, a droplet extractor, and a device for isotachophoresis. The mixing and gradient formation units were incorporated into a device for analysis of nitrate in tap water with standard addition as a single run and multiple depth detection cells to provide an extended linear range.
positive structures (templates for soft lithography). The colorless resin’s good light transmittance (>60% transmission at wavelengths of >430 nm) allows for on-chip optical detection, while the electrically insulating material allows electrophoretic separations. To demonstrate its applicability in microfluidics, the printer was used for the fabrication of a micromixer, a gradient generator, a droplet extractor, and a device for isotachophoresis. The mixing and gradient formation units were incorporated into a device for analysis of nitrate in tap water with standard addition as a single run and multiple depth detection cells to provide an extended linear range.
History
Journal
Analytical chemistryVolume
86Issue
6Pagination
3124 - 3130Publisher
American Chemical SocietyLocation
Washington, D.C.Publisher DOI
ISSN
0003-2700eISSN
1520-6882Language
engPublication classification
C Journal article; C1.1 Refereed article in a scholarly journalCopyright notice
2014, American Chemical SocietyUsage metrics
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