File(s) under permanent embargo
Deficient motor timing in children with neurofibromatosis type 1
journal contribution
posted on 2014-11-01, 00:00 authored by J Debrabant, E Plasschaert, Karen CaeyenberghsKaren Caeyenberghs, G Vingerhoets, E Legius, S Janssens, H Van WaelveldeNeurofibromatosis type 1 (NF1) is one of the most common single-gene disorders affecting fine and visual-motor skills. This case-control study investigated motor timing as a possible related performance deficit in children with NF1. A visual-motor reaction time (VRT) test was administered in 20 NF1 children (mean age 9 years 7 months) and 20 age- and gender-matched typically developing (TD) children. Copying and tracing performance were evaluated using the Beery-Buktenica Developmental Test of Visual-Motor Integration (Beery VMI). Children with NF1 responded with an increased reaction time (RT) to temporally predictive stimuli compared to TD children, whereas RT at unpredictive stimuli did not differ between groups. Motor timing indexed by the RT decrease at predictive stimuli significantly associated with the Beery VMI copy and tracing outcomes. Deficient motor timing as an actual symptom may add to further research on the pathogenesis of NF1-associated motor impairment and the development of more effective treatment. © 2014 Elsevier Ltd.
History
Journal
Research in Developmental DisabilitiesVolume
35Issue
11Pagination
3131 - 3138Publisher
ElsevierLocation
Amsterdam, The NetherlandsPublisher DOI
ISSN
0891-4222eISSN
1873-3379Language
engPublication classification
C1 Refereed article in a scholarly journalUsage metrics
Categories
No categories selectedKeywords
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC