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Delving into disability in Crohn's disease: dysregulation of molecular pathways may explain skeletal muscle loss in Crohn's disease.

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journal contribution
posted on 01.07.2014, 00:00 authored by D R van Langenberg, Paul Della GattaPaul Della Gatta, Briony Hill, Evelyn ZacharewiczEvelyn Zacharewicz, P R Gibson, Aaron RussellAaron Russell
In Crohn's disease (CD), skeletal muscle mass and function are reduced compared to healthy controls, potentially resulting in disability. Mechanisms contributing to muscle impairment, and thus potential therapeutic targets, are poorly understood. This study aimed to measure and compare skeletal muscle size and molecular targets involved in skeletal muscle growth, in CD subjects and healthy controls.

History

Journal

Journal of Crohn's and Colitis

Volume

8

Issue

7

Pagination

626 - 634

Publisher

Elsevier

Location

Amsterdam, The Netherlands

eISSN

1876-4479

Language

eng

Publication classification

C Journal article; C1 Refereed article in a scholarly journal

Copyright notice

2014, Elsevier