Delving into disability in Crohn's disease: dysregulation of molecular pathways may explain skeletal muscle loss in Crohn's disease.
journal contributionposted on 2014-07-01, 00:00 authored by D R van Langenberg, Paul Della GattaPaul Della Gatta, Briony Hill, Evelyn ZacharewiczEvelyn Zacharewicz, P R Gibson, Aaron RussellAaron Russell
In Crohn's disease (CD), skeletal muscle mass and function are reduced compared to healthy controls, potentially resulting in disability. Mechanisms contributing to muscle impairment, and thus potential therapeutic targets, are poorly understood. This study aimed to measure and compare skeletal muscle size and molecular targets involved in skeletal muscle growth, in CD subjects and healthy controls.
JournalJournal of Crohn's and Colitis
Pagination626 - 634
LocationAmsterdam, The Netherlands
Publication classificationC Journal article; C1 Refereed article in a scholarly journal
Copyright notice2014, Elsevier
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