Background: Workplace participation for people with ID is a major policy issue, with both economic and social imperatives. Policy reforms in Australia associated with the implementation of the National Disability Insurance Scheme (NDIS) require new and innovative approaches to address these problems. Objective: This project was established to investigate how a Social Enterprise Framework could be used as a mechanism to transform supported employment services (Australian Disability Enterprises) into open employment settings that secure meaningful, rewarding, and sustainable employment for people with ID. Methods: A systematic literature review was undertaken, and a model of Social Enterprise was developed that would be inclusive of people with ID. The theoretical model was reviewed by industry experts and refined. Its practical application and feasibility was then tested through the implementation of an organisational audit and strategic planning exercise. This was designed to produce an enterprise model. Results: Social Enterprise is an umbrella term describing any organisation that focuses on social change. For people with ID, its essential features include an economically viable business, which provide the payment of 'a living wage', in a setting involving meaningful work that includes opportunities for the acquisition of socially valued skills and career development, as well as contributing to the person's opportunities for social relationships. Conclusion: Though a challenging undertaking, Social Enterprise provides a promising employment option for some people with ID, when such initiatives are driven from executive and senior personnel of an organisation.